Um modelo biomecânico para a resposta do sistema imune à inflamação do ventrículo esquerdo incluindo efeitos de remodelagem e crescimento

Authors

  • Isabela Alves Campice de Oliveira Universidade Federal de Juiz de Fora
  • Marcelo Lobosco Universidade Federal de Juiz de Fora
  • Rodrigo Weber dos Santos Universidade Federal de Juiz de Fora
  • Bernardo Martins Rocha Universidade Federal de Juiz de Fora

Keywords:

Computational mechanics, growth, remodeling, finite element method, biomechanics.

Abstract

This article addresses the cardiac biomechanical response with growth during cardiac muscle inflammation. Biological tissue reacts to stimuli through growth and remodeling, with special relevance in the heart due to heart disease. This study presents a mathematical model that describes the cardiac biomechanical response during inflammation, considering the diffusion of cytokines and the hypertrophy caused by them. The model uses continuous and volumetric growth mechanics, coupled with a cytokine diffusion model. Computational experiments are performed to demonstrate the proposed approach. This work presents a new model that may be useful to understand the complex mechanisms associated with the biomechanical responses of the heart in inflammatory conditions, contributing to the field of biomechanics.

References

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Published

2024-01-31

Issue

Vol. 9 No. 2 (2023): Revista Interdisciplinar de Pesquisa em Engenharia

Section

Artigos

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How to Cite

Um modelo biomecânico para a resposta do sistema imune à inflamação do ventrículo esquerdo incluindo efeitos de remodelagem e crescimento. (2024). Revista Interdisciplinar De Pesquisa Em Engenharia, 9(2), 57-65. https://periodicostestes.bce.unb.br/index.php/ripe/article/view/52303